#cancerresearch#astrocytomas#clinicalresearch#brain#spinalcord
#neurons#healthcare#neurosurgery#cancertreatments
A team of researchers from the Nagoya University Graduate School of Medicine has reported that patients with a rare form of brain and spinal cord cancer, localized isocitrate dehydrogenase wild-type (IDHwt) histologically diffuse astrocytoma, have a poor prognosis similar to the most malignant types of brain and spinal cord tumors. Their findings, published in the journal Scientific Reports, point to the need for strong postoperative care for patients with this type of tumor.
In 2016, to improve prognosis and patient management, the WHO classification of central nervous system tumors included a new classification of ‘diffuse gliomas’, based on the presence
or absence of specific mutations. Two rare types of diffuse astrocytomas are infiltrative and localized isocitrate dehydrogenase wild-type (IDHwt) diffuse astrocytomas. Since they are so rare, there is a lack of information on whether the infiltrative or localized characteristics affect
their prognosis and what this means for the patient.
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