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00:00:49 1 Application
00:01:45 2 Scope
00:02:57 3 History
00:03:15 4 Chemical structure and thermodynamics
00:03:25 4.1 Thermochemistry
00:04:54 4.2 Conformational analysis
00:07:04 4.3 Non-covalent interactions
00:08:29 4.4 Acid–base chemistry
00:09:32 5 Kinetics
00:10:30 5.1 Rate laws
00:11:29 5.2 Catalysis
00:12:16 5.3 Kinetic isotope effect
00:13:16 5.4 Substituent effects
00:15:19 5.5 Solvent effects
00:17:14 6 Quantum chemistry
00:22:24 7 Spectroscopy, spectrometry, and crystallography
00:23:27 7.1 NMR and EPR spectroscopy
00:25:24 7.2 Vibrational spectroscopy
00:27:16 7.3 Electronic excitation spectroscopy
00:28:12 7.3.1 Mass spectrometry
00:29:52 7.3.2 Crystallography
00:31:24 8 Further reading
00:31:33 8.1 General
00:33:40 8.2 History
00:34:26 8.3 Thermochemistry
00:36:06 9 See also
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"There is only one good, knowledge, and one evil, ignorance."
- Socrates
SUMMARY
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Physical organic chemistry, a term coined by Louis Hammett in 1940, refers to a discipline of organic chemistry that focuses on the relationship between chemical structures and reactivity, in particular, applying experimental tools of physical chemistry to the study of organic molecules. Specific focal points of study include the rates of organic reactions, the relative chemical stabilities of the starting materials, reactive intermediates, transition states, and products of chemical reactions, and non-covalent aspects of solvation and molecular interactions that influence chemical reactivity. Such studies provide theoretical and practical frameworks to understand how changes in structure in solution or solid-state contexts impact reaction mechanism and rate for each organic reaction of interest.
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