The Manchester derby promises to be a thrilling clash between two teams struggling for form. Manchester City, who have won five of the last six league encounters, face a United side in desperate need of a win after two consecutive losses under new manager Ruben Amorim. Manchester City’s recent dip in form has become a real crisis for Pep Guardiola. Will Manchester United add to his problems?

Elsewhere, leaders Liverpool host Fulham, Chelsea faces Brentford in a west London derby, Tottenham Hotspur head down to Southampton, and a key 6-pointer awaits Wolves, who host Ipswich. All this and more on this week's Premier League Preview.

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