The last 5-10 years has been a very exciting time for the treatment of myeloid malignancies, with great advances in targeted therapies. Amir Fathi, MD, of the Dana-Farber Cancer Institute, Boston, MA, discusses therapy targeting isocitrate dehydrogenase (IDH) in acute myeloid leukaemia (AML). Dr Fathi highlights studies which hare evaluating IDH inhibitors as a monotherapy or in combination with other types of treatment, for which the preliminary data is promising. This interview was recorded at the American Society of Hematology (ASH) 2017 Annual Meeting and Exposition in Atlanta, GA.

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