00:18 Cell Biology
2:33 Dietary Sources
3:45 Obesity
4:36 Diabetes
5:36 Neuropathy
7:15 Hypertension
8:14 Multiple Sclerosis
10:00 Covid-19
10:53 Side Effects

Lipoic acid is a very popular nutritional supplement. In this video, I’ll explain what it is, the biological effect in the cell, and the results of numerous randomized controlled trials in obesity, diabetes, hypertension, multiple sclerosis, neuropathy, and even covid-19

Sources:

Oregon State University article on lipoic acid: [ Ссылка ]
Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type I and type II diabetes mellitus: A systematic review and meta-analysis: [ Ссылка ]
Lipoic acid in secondary progressive MS A randomized controlled pilot trial: [ Ссылка ]
Determination of free α-lipoic acid in foodstuffs by HPLC coupled with CEAD and ESI-MS: [ Ссылка ]
Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis: [ Ссылка ]
Efficacy and safety of oral alpha-lipoic acid supplementation for type 2 diabetes management: a systematic review and dose–response meta-analysis of randomized trials: [ Ссылка ]
A Randomized, Single-Blind, Group Sequential, Active-Controlled Study to Evaluate the Clinical Efficacy and Safety of α-Lipoic Acid for Critically Ill Patients With Coronavirus Disease 2019 (COVID-19): [ Ссылка ]
The effects of alpha lipoic acid (ALA) supplementation on blood pressure in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials: [ Ссылка ]
R- Is Superior to S-Form of α-Lipoic Acid in Anti-Inflammatory and Antioxidant Effects in Laying Hens: [ Ссылка ]
Article on “lipoic acid supplement” without the product: [ Ссылка ]
α-Lipoic Acid and Insulin Autoimmune Syndrome: [ Ссылка ]


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Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.

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he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.

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