(6 Oct 2014) RESTRICTION SUMMARY: AP CLIENTS ONLY
SHOTLIST
AP TELEVISION - AP CLIENTS ONLY
London, United Kingdom - 6 October 2014
1. US-British Nobel Prize for medicine winner John O'Keefe writing on blackboard
2. O'Keefe standing in room
3. SOUNDBITE (English) John O'Keefe, Nobel winner:
"So I got a call from the centre director - Alex - who said there's a gentleman from Stockholm who would like to have a word with you and he says it's rather urgent. So I thought, 'I wonder what he wants to talk to me about?'. And in fact it was the secretary of the Nobel committee and he told me the news when I called him."
4. Cutaway of hands
5. SOUNDBITE (English) John O'Keefe, Nobel winner:
"I think every scientist somewhere in the back of their head knows that around October some things are happening. So I was surprised of course, and was very pleased, and honoured. But I have to admit before I called him I took a very long deep breath. But I was thrilled, yeah."
6. Wide of O'Keefe in interview
"You need to find your way around the world, you need a map, you need to know where you are on the map, you need to know which way is north, you need to know how far the distance, you need to know how far apart places are. So we suggested there might be these other cells and certainly they have now been found. And one of the very important findings, which is honoured by this prize, was by the Mosers (Edvard and May-Britt, the two other Nobel Prize recipients) to find the cells they call 'grid cells', which look to us at least in certain circumstances that they might be providing just exactly that metric. The way of knowing how far you're going in a particular direction."
8. Cutaway of hands
9. SOUNDBITE (English) John O'Keefe, Nobel winner:
"Of course it's terrific. I have to say I made the initial discovery over 40 years ago. It was met then with a lot of scepticism and that's not unusual in science. And then slowly over years the evidence accumulated, and I think it's a sign of recognition not only for myself and the work I did, but for the way in which the field has bloomed and expanded. When I started there were very, very few people who were doing that sort of work and now there are laboratories all over the world, and I think this is, the honour is as much for the field as it is for me personally."
10. O'Keefe standing in room after interview
STORYLINE
A US-British scientist said on Monday he was was "surprised and honoured" when he got the news that he had won 2014's Nobel Prize for medicine.
75-year-old John O'Keefe's work in the 1970s paved the way for the discovery of the brain's navigation system - the inner GPS that helps us find our way in the world.
O'Keefe, who now works at London's University College London, discovered the first component of this system in 1971 when he found that a certain type of nerve cell was always activated when a rat was at a certain place in a room.
He demonstrated that these "place cells" were building up a map of the environment, not just registering visual input.
Thirty-four years later, in 2005, May-Britt Moser and Edvard Moser, married neuroscientists at the Norwegian University of Science and Technology in Trondheim, identified another type of nerve cell.
The "grid cell" generates a coordinate system for precise positioning and path-finding, the Nobel Assembly said on Monday.
They added that the combined research represented a "paradigm shift" in neuroscience that could help researchers understand the sometimes severe spatial memory loss associated with Alzheimer's disease.
===========================================================
Find out more about AP Archive: [ Ссылка ]
Twitter: [ Ссылка ]
Facebook: [ Ссылка ]
Instagram: [ Ссылка ]
You can license this story through AP Archive: [ Ссылка ]
