Breaking News! A DNA vaccine has been developed that could be a game changer for HER2 positive breast cancer patients.

A phase 1 Trial published in the JAMA oncology tested the vaccine on 66 women with metastatic disease.[ Ссылка ]

Chapters
00:00 Introduction
00:25 Take home message (if you want to skip the rest of the video)
00:44 What was the study about
00:56 What is the HER2 receptor?
01:27 Why was the vaccine invented?
02:07 Who did they test the vaccine on?
03:01 What were the trial results?
03:58 What happens next?

The vaccine encourages the body to mount an immune response to breast cancer cells that over-express the HER2 receptor.

The study showed that the vaccine was safe - with only minor side effects similar to the Covid vaccine. But it also showed that over ten years, 80% of the women were still alive (only 50% were expected to live that long).

A phase II trial is now going ahead to test the vaccine on a larger group of patients, and in the years to come, there could be a possible treatment and even cure for HER2+ breast cancer patients. Similar trials are also being done with vaccines for TNBC patients.

Let me know if you've got any further questions











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