#Mumps is a viral infection of the salivary glands primarily involving the parotid gland hence given the name epidemic parotitis.
The infection is caused by a single stranded RNA virus in the family paramyxoviridae.
Over the viral envelop the virus has 2 glycoproteins namely the NH or neuraminidase and hemagglutinin protein responsible for attachment of viral cell to a host cell and the F or fusion proteins which are responsible for fusion of viral and the host cell membranes hence allowing entrance of the viral RNA into the host cell resulting in multiplication of viral cells within host cells.
Humans are the only natural host of the mumps virus. The virus is primarily transmitted by respiratory secretions such as respiratory droplets and saliva, as well as via direct contact with an infected person. Transmission can occur from one week before the onset of symptoms to eight days after the symptoms have appeared. During infection, the virus first infects the upper respiratory tract. From there, it spreads to the salivary glands and lymph nodes. Infection of the lymph nodes lead to presence of the virus in blood, which spreads the virus throughout the body. Mumps infection is usually self-limiting which means that the disease comes to an end after the immune system clears the infection.
Video (diagrams+editing) & Voiceover:
Dr.Maryam Kazman
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