Analysing biological samples is a key aspect of understanding the nature of a patient’s disease and prescribing the appropriate treatment. In this interview, recorded at the 2017 National Cancer Research Institute (NCRI) Conference, Andrew Beggs, FRCS (Gen), PhD, of the University of Birmingham, Birmingham, UK, outlines his lab's work investigating analytical techniques for studying patient samples. These include being able to analyze formalin-fixed paraffin-embedded (FFPE) samples to comparable levels of detail to fresh samples, identifying circulating tumor (ct)DNA through methylation patterns and determining immunotherapy candidates through genome sequencing.
Recent developments in DNA sequencing
Теги
Speaker: Andrew BeggsEvent: NCRI 2017Subject: GeneralsequencingDNAformalin-fixedhistological samplesexome sequencingWESDNA methylationmethylation assaygenomeclinical trialsdiseasecirculating tumor DNAnext-generation sequencinggenetic markerstumor mutation burdenimmunotherapyctDNANGSFormat: Interview10000 genomes projectadvances