Data from the Phase III MURANO study (NCT02005471) in relapsed/refractory chronic lymphocytic leukemia (CLL) was highly anticipated at the American Society of Hematology (ASH) 2017 Annual Meeting and Exposition in Atlanta, GA. Here, George Follows, BMBCh, PhD, FRCP, FRCPath, of Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK, provides an update on this study and how he anticipates the results will change the treatment of CLL.
MURANO study: exciting times in CLL
Теги
Speaker: George FollowsEvent: ASH 2017Format: InterviewSubject: Chronic Lymphocytic LeukemiaSubject: LeukemiaTrial: MURANOMedicines: VenetoclaxMedicines: RituximabMedicines: BendamustineField: TreatmentNCT02005471clinical trialscombination therapytargeted therapyCLLPhase IIItoxicityside effectstumor lysis syndromedepth of responsePFSoverall survivaloverall response rateORRcomplete responseBCL-2BCL-2 inhibitor