With Prof. YoonJoo Choi, Dr. Peng Li, Dr. Jennifer Malcolm, Mr. Narasimha Rao.

Professor Yoonjoo Choi is based at Chonnam National University Medical School in Korea. His work focuses on the development and application of computational methods for biological and immunological problems, in the context of protein sequence/structure/function studies. His primary focus has been structure-based computational modeling and computationally-driven engineering of the immune response to foreign proteins, in the contexts of both desired responses in infection/vaccination and undesired responses to therapeutics.

Dr. Jennifer Malcolm completed her BSc/Hons in Microbiology at Glasgow Caledonian University, where she first sparked an interest in host-pathogen interactions in health and disease. She pursued this interest during her PhD at the University of Glasgow, School of Medicine, Dentistry and Nursing, where she identified how oral biofilm development in young children is accompanied by maturation of salivary immune responses. Following her PhD, she worked as a Post-Doctoral Research Associate at the University of Glasgow, School of Infection and Immunity. Here she identified novel therapeutic targets for the treatment of periodontitis and began her work investigating mechanisms driving autoimmunity in rheumatoid arthritis. In 2018, she took up a teaching position at the University of Glasgow Dental School. Here, she presents data exploring how oral bacteria exploit innate immunity to subvert adaptive immune responses, and how this impacts the maintenance of immune tolerance in the oral mucosa.

Dr. Peng Li is a Cancer Immunology Scientist at Eisai in Japan. Dr. Peng moved from his home China, Xi’an to Japan in 2010 to pursue his education and has obtained his Ph.D at the University of Tokyo in 2017 where he studied the Immunology of inflammatory bowel disease at the department of Applied Biological Chemistry. During his Ph.D, he went on as a visiting research fellow at the University of Nottingham, UK in 2016 to research Chronic obstructive pulmonary disease (COPD) at the medical school. Following his Ph.D, he completed his postdoc at Kyoto University Medical School in 2019 working on cancer immunology research in Honjo’s Lab that won the 2018 Nobel Prize in physiology or medicine. He then joined Eisai in 2019 as a scientist in cancer immunology research. In this talk, Dr. Li will be sharing with us their strategy for immunogenicity risk assessment for the development of antibody therapeutics that includes the use of ProImmune's ProScern DC-T cell assay.

Narasimha Rao is a Senior Scientist, Global Clinical Management function of Dr. Reddy’s laboratories limited. He obtained Master’s degree in Biotechnology in year 2006 from University of Madras, India and started his career as a research officer in Virology R&D in Vaccine Manufacturing , and currently works at Dr. Reddy’s, a leading multinational pharmaceutical company based in India. Since 2010 he has worked on pre-clinical assessment of high value therapeutic products/small molecules, drug repositioning and drug discovery programs and is currently investigating the immunogenicity of complex therapeutic generic peptides.

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