This podcast episode features an in-depth conversation on metabolic therapies and their potential in cancer treatment, particularly focused on glioblastoma and other glycolytic cancers. Our guest, Dr Dom D'Agostino, a researcher and professor with a diverse background in neuroscience, molecular pharmacology, nutrition and physiology, has a particular interest in metabolic therapies. Dr Dom shares how manipulating the body’s metabolism through the glucose ketone index (GKI), therapeutic ketogenic diets, and redox therapies can improve cancer outcomes by reducing tumour growth and enhancing standard treatments like chemotherapy and radiation. We also explore the synergies of non-toxic therapies such as hyperbaric oxygen, metformin, and IV vitamin C, and how these could potentially reduce the side effects and overall outcomes of cancer treatment.

We cover:
🩺 Standard cancer care with and without metabolic interventions (e.g. ketogenic diet)
⚙️ Non-toxic therapies for glioblastoma including hyperbaric oxygen therapy
💊 Managing seizures with ketogenic therapies - a superior alternative to anti-seizure drugs
🍽 The power of fasting and the importance of protein intake in chemotherapy and cancer augmentation
🔥 Why certain cancers are more susceptible to metabolic-based therapies
🔬 How overall mitochondrial health dictates cancer cell transformation

Dom also touches on the fundamental relationship between liver health and cancer growth and metabolic strategies to prevent cancer. If you're interested in the intersection of nutrition and cancer or wondering how far we are from keto becoming part of standard care, this is a must-listen episode with Dr Dom!

Find Dom:
Website [ Ссылка ]
Metabolic Health Summit [ Ссылка ]
Metabolic Health Summit YouTube [ Ссылка ]

Mentioned in this episode:
Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States, 2019 - [ Ссылка ]
Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy [ Ссылка ]
Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation [ Ссылка ]
Book - Cancer as a Metabolic Disease by Thomas Seyfried
[ Ссылка ]
The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer [ Ссылка ]
Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer 10.1002/ijc.28809
Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet [ Ссылка ]
Tripping Over the Truth by Travis Christofferson [ Ссылка ]
Clinical trials in progress [ Ссылка ]
Patients with a Kabuki syndrome phenotype demonstrate DNA methylation abnormalities [ Ссылка ]
Books - Good energy by Casey Means [ Ссылка ]
[ Ссылка ]
Total recall by Arnie [ Ссылка ]

If you enjoy this, you may also be interested in our episode with Mary Newport, M.D. | Brain Fuel: How Coconut Oil and MCTs Can Transform the Alzheimer's Brain

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