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What causes high reverse T3 (rT3)?

Well the simple answer is cortisol. But let's dive in…..because this has NOTHING to do with the thyroid itself and warrants no thyroid medication. In rare cases, sometimes people are put on T4 and they don’t need it, or take thyroid glandulars, which can drive up rT3

rT3 is virtually inactive having only 1% the activity of T3. But when active, its a T3 antagonist binding to T3 receptors blocking the action of T3 and thus acting as a metabolic break. Normal metabolism of T4 requires the production of the appropriate ratio, or balance, of T3 to rT3. If the proportion of rT3 dominates then it will antagonize T3 thus producing hypothyroid like symptoms despite sufficient circulating levels of T4 and T3, and perfect labs.

How does this happen: The culprit is always chronic stress, “starvation,” poor blood sugar management (over eating carbs, underrating protein, poor food frequency)…the end results excess cortisol to try to meet the bodies needs, because you are not. We could essential say, this is more of an adrenal issue, vs a thyroid issue if you want to categorize it.

Periods of prolonged stress will cause an increase in cortisol levels as the adrenal glands respond to the stress. The high cortisol levels inhibit the 5-deiodinase enzyme Type 1 and thus the conversion of T4 into T3, thus reducing active T3 levels. The conversion of T4 is then shunted towards the production of the rT3 via the 5-deiodinase enzyme Type 3.

There are no supplements or medications needed for this, NONE. This all has to do with living in a way, eating in a way, and thinking in a way to support your metabolic needs daily. Thus taking the burden off your adrenals (because now you are meeting your needs), decreasing inhibition of 5-deodinase = decreasing the shunting of T4 to rT3 = freeing up T3 receptor sites = decreasing thyroid like symptoms and rT3 levels.

Always food first.
Always cause and effect.
Change the cause, don’t chase the effect.

Not medical advice.
#reverset3syndrome #reverset3dominance #reverset3hypothyroidism #thyroidtips #thyroidnsupport #hypothyroidism #hypothyroidtips #hypothyroidsupport #nosupplementsneeded.

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