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Preparation of Mesh-Shaped Engineered Cardiac Tissues Derived from Human iPS Cells for In Vivo Myocardial Repair - a 2 minute Preview of the Experimental Protocol

Takeichiro Nakane, Mosha Abulaiti, Yuko Sasaki, William J. Kowalski, Bradley B. Keller, Hidetoshi Masumoto
RIKEN Center for Biosystems Dynamics Research, Clinical Translational Research Program; Kyoto University, Department of Cardiovascular Surgery, Graduate School of Medicine; Cell and Developmental Biology Center, National Institutes of Health, Laboratory of Stem Cell and Neuro-Vascular Biology; University of Louisville, Kosair Charities Pediatric Heart Research Program, Cardiovascular Innovation Institute; University of Louisville, Department of Pediatrics, School of Medicine; Mitsubishi Kyoto Hospital, Department of Cardiovascular Surgery; Cincinnati Children's Heart Institute,;

The present protocol generates mesh-shaped engineered cardiac tissues containing cardiovascular cells derived from human induced pluripotent stem cells to allow the investigation of cell implantation therapy for heart diseases.

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