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Cells in your body don’t exist as isolated units; they talk to each other, and correct intercellular communication is essential for your health. Unfortunately, intercellular communication goes south as you get older, and that’s one of the reasons we wind up getting a bunch of nasty diseases later in life. Can we fix that? Possibly!
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Stock contents: Shutterstock, Videoblocks
Music:
Intro jingle courtesy of Kevin MacLeod - Incompetech.com
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Sources:
The Hallmarks of Aging
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The hallmarks of aging. Cell, 153(6), 1194-1217.
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Parabiosis
Loffredo, F. S., Steinhauser, M. L., Jay, S. M., Gannon, J., Pancoast, J. R., Yalamanchi, P., ... & Miller, C. M. (2013). Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy. Cell, 153(4), 828-839. ([ Ссылка ])
Villeda, S. A., Luo, J., Mosher, K. I., Zou, B., Britschgi, M., Bieri, G., ... & Lucin, K. M. (2011). The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature, 477(7362), 90.
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Rebo, J., Mehdipour, M., Gathwala, R., Causey, K., Liu, Y., Conboy, M. J., & Conboy, I. M. (2016). A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood. Nature communications, 7, 13363.
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Dr. Irina Conboy: Could Filtering Our Aged Blood Keep us Young? ([ Ссылка ])
Alkahest clinical trials
Clinicaltrials.gov ([ Ссылка ]=)
Alkahest
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Rejuvenation Roadmap
[ Ссылка ]
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#Inflammation #Aging #Inflammaging #Parabiosis #MolecularBiology #Biology #LifeExtension
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