At the fourth annual Americans Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 2019 held in Dallas, Texas, Antje Bischof, MD, University of California, San Francisco, presented research that found that upper cervical cord atrophy obtained from routine brain MRI is a strong indicator of impending conversion from relapsing-remitting multiple sclerosis (MS) to secondary progressive MS (SPMS)
Bischof and colleagues conducted a longitudinal study that evaluated spinal cord atrophy measured in patients with MS through MRI over 12 years. Fifty-four patients with relapsing-remitting MS who converted to SPMS during the observation period were matched based on certain demographic and clinical criteria to 54 subjects with relapsing-remitting MS who remained relapsing-remitting MS during the observation period. Additionally, 54 age- and sex-matched healthy controls were evaluated at baseline.
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