Receptor tyrosine kinases or RTK are enzyme linked receptors that are involved in signaling pathways. Like GPCRS they are also receptors but in receptor tyrosine kinases the receptor is attached to an enzyme unlike g protein coupled receptors where receptor is linked to G protein. Phosphorylation plays a very important role in activating the RTKs or receptor tyrosine kinases. Binding of the legand leads to the dimerisazation of the receptors in RTKs. The activated receptor allows the coming closure of two cytosolic domains of receptors towards each other.
GPCR signaling pathway links
1. Introduction to cell signaling
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2. Basic mechanism of cell signaling
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3. Types of cell signaling
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4. GPCR functioning mechanism
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5. PKA regulation of glycogen metabolism
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6. 1st part cAMP pathway :
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7. 2nd part cAMP pathway
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Receptor Tyrosine Kinases (RTK) | RTK Signaling |
Теги
bmh learningreceptor tyrosine kinasesreceptor tyrosine kinase activationreceptor tyrosine kinase animationreceptor tyrosine kinase dimerizationreceptor tyrosine kinase functionreceptor tyrosine kinase mechanismreceptor tyrosine kinase pathwayreceptor tyrosine kinase phosphorylationreceptor tyrosine kinase signallingrtk signalingwhy rtk dimerizetyrosine kinase receptormechanism of receptor kinaseenzyme linked receptorsrtk signaling pathway
