What are high risk medicines?
Medicines with a high potential for causing patient injury or harm due to misuse or error are defined as high-risk medicines (in the USA and some other countries, these are known as high alert medications).

When high risk medicines are used in error or administered incorrectly (as compared to other medicines), there is an increased likelihood of causing severe harm/serious side effects to the patient.


Lists of high risk medicines



High Risk Medicine Group

Examples

Lists of high risk medicines
Aminoglycosides

Gentamicin, amikacin, tobramycin, streptomycin

Anticoagulants

Oral anticoagulants: warfarin, apixaban, dabigatran, edoxaban, rivaroxaban

Parenteral anticoagulants: heparin, low molecular weight heparins (enoxaparin, dalteparin, tinzaparin)

Antihypertensives

Angiotensin-converting enzyme (ACE) inhibitors: ramipril, perindopril, lisinopril

Angiotensin-II receptor blockers: irbesartan, losartan, candesartan

Antiplatelet drugs

Aspirin, clopidogrel

Benzodiazepines

Diazepam, alprazolam, temazepam, lorazepam

Non-steroidal anti-inflammatory drugs (NSAIDs)

Ibuprofen, indometacin, ketoprofen

Hypoglycaemic drugs including insulin

Sulfonylureas: Gliclazide, tolbutamide, glimepiride

Biguanide: Metformin

Thiazolidinedione: Pioglitazone

Alpha-glucosidase inhibitor: Acarbose

Meglitinide: Repaglinide

Dipeptidyl peptidase-4 (DPP-4) inhibitors: Alogliptin, linagliptin, sitagliptin, saxagliptin, vildagliptin

Sodium-glucose co-transporter 2 (SGLT2) inhibitors: Canagliflozin, dapagliflozin, empagliflozin, ertugliflozin






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