Welcome to our YouTube video discussing the PALMIRA clinical trial with Dr. Javier Cortés and Dr. Antonio Llombart. PALMIRA is an international, multicenter, randomized, open-label, Phase II clinical trial aimed at evaluating the efficacy and safety of continuing palbociclib in combination with second-line endocrine therapy for hormone receptor-positive/HER2-negative advanced breast cancer patients who have experienced clinical benefit during first-line palbociclib-based treatment.

The primary objective of this study is to compare the efficacy, measured by progression-free survival (PFS), between continuation of palbociclib treatment combined with second-line endocrine therapy (fulvestrant or letrozole) and endocrine therapy alone in pre- and post-menopausal women with HR-positive/HER2-negative advanced breast cancer. Additionally, the trial aims to explore potential molecular markers of sensitivity and/or resistance for the combination therapy and endocrine therapy alone.

Join us as we delve into the details of the PALMIRA study, highlighting its significance in advancing treatment options for patients with advanced breast cancer. Don't miss this opportunity to learn about the latest advancements in clinical research and the potential impact on patient outcomes.

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