Statins are effective and reliable when it comes to regulating ‘bad’ cholesterol, but some people complain of muscle pain after taking the drugs.
New research led by Cleveland Clinic's Dr. Steven Nissen is aimed at providing more solutions for treating statin-intolerant patients. Dr. Nissen says it’s an issue that can be frustrating for both patients and physicians.
Researchers examined a group of almost five-hundred patients worldwide who had reported statin intolerance.
Patients received either a statin or a sugar pill and then switched after ten weeks.
They found that forty-two percent actually produced symptoms from the statin and not from the placebo.
Dr. Nissen says that the study has important implications because researchers were able to show objective evidence of muscle-related statin intolerance.
The next goal was to find out which drug treatments could work for those patients who were truly statin-intolerant.
The second portion of the trial involved testing two non-statin cholesterol lowering drugs – an oral drug that blocks the absorption of cholesterol in the gastrointestinal tract, and a newer injectable drug.
While both of the drugs were well tolerated, the newer injectable drug showed better results for lowering ‘bad’ cholesterol.
Dr. Nissen says the good news is that more folks who may have thought they couldn’t take statins before might actually be able to take them and that for those who truly can’t, there is a really good alternative.
For more details, visit newsroom.clevelandclinic.org.
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