The ability to maintain normal psychological and physical functioning and avoid serious mental illness when exposed to stress and trauma (such as consequences of post-traumatic stress disorder), a phenomenon known as resilience, is a topic that has been investigated over the past several years with increasing attention. At the Center for Molecular Integrative Neuroresilience, Dr. Pasinetti and his team are working to understand the molecular mechanisms linking the gut-brain axis, to identify specific gut microbes, also known as new-generation probiotics, to influence therapeutic efficacy of novel drug and natural compounds used to treat neuropsychiatric and age-related neurodegenerative disorders, including dementia.
