Sung-Bae Kim, MD, PhD, Asan Medical Center, Seoul, South Korea, discusses the updated results from the Phase III DESTINY-Breast02 trial (NCT03523585) of trastuzumab deruxtecan (T-DXd) against physician’s choice in patients with HER2+ metastatic breast cancer previously treated with trastuzumab emtansine (T-DM1). Progression-free survival and overall survival were still significantly improved in patients receiving T-DXd and adverse events remain manageable in this cohort. This interview took place at the 2024 European Society for Medical Oncology (ESMO) Breast Cancer Annual Congress in Berlin, Germany.

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