In this video, Jonathan Kaufman, MD, Winship Cancer Institute, Emory University, Atlanta, GA, discusses two main challenges associated with treating frail, older patients with multiple myeloma. The first challenge is how to treat high-risk patients, and Dr Kaufman notes that the ideal treatment for this patient population has not yet been identified. The second challenge is management of toxicities, particularly related to dexamethasone. Dr Kaufman explains that reducing dexamethasone dosing or removing dexamethasone entirely from treatment may be viable options, and cites researching evaluating these approaches. This interview took place at the 9th World Congress on Controversies in Multiple Myeloma (COMy) 2023, held in Paris, France.
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