The Ohio State University Wexner Medical Center is a national leader in performing autologous chondrocyte implantation (ACI), a unique technique that can address a defect or hole in the cartilage of the knee (the protective covering of the bone).

Dr. David Flanigan, the director of Ohio State Sports Medicine's cartilage restoration program, explains the steps of ACI and how our physicians approach it.

ACI provides pain relief from larger areas of cartilage damage and cartilage injuries. ACI is a three-stage procedure:

Stage 1: Cells are taken from another part of the patient’s knee.
Stage 2: The cells are grown in vitro for about four to six weeks.
Stage 3: The cells are reintroduced into the affected area in the knee under a patch, ultimately forming new cartilage.

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