In the latest episode of Daily Value, we look at new research on creatine monohydrate's potential to enhance cognitive function, based on a recent meta-analysis published in Frontiers in Nutrition (PMID: 39070254). Traditionally used for its athletic performance benefits, creatine is now emerging as a promising supplement for brain health and cognitive enhancement.
Talking Points:
*Does creatine supplementation enhance cognitive function(s)?
*Theoretical mechanisms: creatine enhances brain ATP levels through phosphocreatine resynthesis, offers neuroprotection against oxidative stress, and may act as a neuromodulator affecting neurotransmitters like acetylcholine.
*Dosing strategies: The episode examines the complexities of optimal dosing protocols, discussing whether short-term high-dose loading or prolonged moderate dosing is more effective for increasing brain creatine concentrations.
*Target populations: gender differences and health status may matter for who will experience more pronounced cognitive benefits from creatine supplementation.
I discuss the practical implications of these findings and discuss whether creatine supplementation is right for you
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