2007 IS250 w/ 78XXX miles. After further inspection, I found out the bearing on the water pump failed. If you are mechanically inclined, you should be able to DIY.
***1/20/14 Update*** DIY Links uploaded below. These guides were not performed by me but props to these guys on Clublexus.com helping us fellow IS250 owners out.
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Actual PDF thanks to Clublexus.com as well
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