The Substance is a 2024 satirical body horror film co-produced, written and directed by Coralie Fargeat. It stars Demi Moore, Margaret Qualley and Dennis Quaid. An international co-production between the United Kingdom, the United States and France, its plot follows a fading celebrity (Moore) who uses a black market drug that temporarily creates a younger version of herself (Qualley), with horrifying side effects.
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