Chafic Karam, MD, University of Pennsylvania, Philadelphia, PA, shares an insight into a talk on understanding other subspecialties when treating patients with amyloidosis, focusing primarily on the neurological aspects of the disease. Patients may present with a host of neurological symptoms, from numbness and tingling (which begins in the feet and progresses to the hands) to dysautonomia-related gastrointestinal (GI) symptoms and subsequent weight loss. In his talk, Dr Karam discussed the techniques used to assess for neuropathy in the clinic and in clinical trials, as well as outlining some biomarkers whose levels may be altered by certain drugs or due to nerve damage. This interview took place at the XIX International Symposium on Amyloidosis (ISA) in Rochester, MN.
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