A study by Melissa Christine Kander and co-authors in USA highlights significant gender differences in cardiovascular health, emphasizing that while males experience myocardial infarctions earlier than females, women face increased cardiovascular risk after menopause. This suggests a potential protective role of estrogen against oxidative stress, which is a key contributor to cardiovascular diseases. Interestingly, females generally show lower susceptibility to oxidative stress, possibly due to estrogen's antioxidant properties and differences in NADPH-oxidase activity. These findings underscore the need to explore gender-specific mechanisms in cardiovascular disease to enhance treatment strategies. Further investigation will lead to tailored therapeutic approaches that consider the unique physiological responses of each gender.

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