Curtain Raiser 25 - Fertility Preservation & ART Part - 2 By Dr. Prof. (Col) Pankaj Talwar, VSM
An interactive video lecture series: Curtain Raiser meant for IVF Doctors, Clinicians, Endocrinologists, Reproductive Medicine Specialists, Embryologists By IVF Specialist - Dr. Prof. (Col) Pankaj Talwar, VSM
𝐅𝐞𝐫𝐭𝐢𝐥𝐢𝐭𝐲 𝐏𝐫𝐞𝐬𝐞𝐫𝐯𝐚𝐭𝐢𝐨𝐧 & 𝐀𝐫𝐭
Fertility preservation and Assisted Reproductive Technologies (ART) play a vital role in safeguarding fertility for individuals undergoing medical treatments or facing other fertility-threatening circumstances.
In this video, we explore various fertility preservation techniques, including oocyte freezing, ovarian transplants, and sperm freezing, to help you make informed decisions about preserving your fertility.
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𝐈𝐧𝐭𝐫𝐨𝐝𝐮𝐜𝐭𝐢𝐨𝐧 𝐭𝐨 𝐅𝐞𝐫𝐭𝐢𝐥𝐢𝐭𝐲 𝐏𝐫𝐞𝐬𝐞𝐫𝐯𝐚𝐭𝐢𝐨𝐧 & 𝐀𝐑𝐓
𝐎𝐨𝐜𝐲𝐭𝐞 𝐅𝐫𝐞𝐞𝐳𝐢𝐧𝐠: 𝐀 𝐩𝐫𝐨𝐦𝐢𝐬𝐢𝐧𝐠 𝐨𝐩𝐭𝐢𝐨𝐧 𝐟𝐨𝐫 𝐰𝐨𝐦𝐞𝐧
• 𝐓𝐡𝐞 𝐩𝐫𝐨𝐜𝐞𝐬𝐬 𝐨𝐟 𝐨𝐨𝐜𝐲𝐭𝐞 𝐟𝐫𝐞𝐞𝐳𝐢𝐧𝐠
• Ovarian stimulation
• Egg retrieval procedure
• Denuding and assessment
• Cryoprotectant addition
• Vitrification technique
• Long-term storage
• 𝐈𝐝𝐞𝐚𝐥 𝐜𝐚𝐧𝐝𝐢𝐝𝐚𝐭𝐞𝐬 𝐟𝐨𝐫 𝐨𝐨𝐜𝐲𝐭𝐞 𝐟𝐫𝐞𝐞𝐳𝐢𝐧𝐠
• Cancer patients pre-treatment
• Delaying childbearing
• Diminished ovarian reserve
• Family history early menopause
• Ethical concerns with embryos
𝐂𝐚𝐧𝐜𝐞𝐫 𝐚𝐧𝐝 𝐅𝐞𝐫𝐭𝐢𝐥𝐢𝐭𝐲 𝐏𝐫𝐞𝐬𝐞𝐫𝐯𝐚𝐭𝐢𝐨𝐧
• 𝐓𝐡𝐞 𝐢𝐦𝐩𝐚𝐜𝐭 𝐨𝐟 𝐜𝐚𝐧𝐜𝐞𝐫 𝐭𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭𝐬 𝐨𝐧 𝐟𝐞𝐫𝐭𝐢𝐥𝐢𝐭𝐲
- Chemotherapy: potential damage to eggs or sperm, may cause premature menopause
- Radiation: potential harm to reproductive organs, may affect hormone production
- Surgery: removal of reproductive organs, may impact fertility directly
• 𝐅𝐞𝐫𝐭𝐢𝐥𝐢𝐭𝐲 𝐩𝐫𝐞𝐬𝐞𝐫𝐯𝐚𝐭𝐢𝐨𝐧 𝐨𝐩𝐭𝐢𝐨𝐧𝐬 𝐟𝐨𝐫 𝐜𝐚𝐧𝐜𝐞𝐫 𝐩𝐚𝐭𝐢𝐞𝐧𝐭𝐬
- Oocyte freezing: preserving a woman's eggs before treatment
- Sperm freezing: preserving a man's sperm before treatment
- Embryo freezing: creating and preserving embryos for future use
- Ovarian tissue cryopreservation (OTC): preserving ovarian tissue containing immature
- Ovary transposition: surgically moving the ovaries away from the radiation field
- Gonadotropin-releasing hormone (GnRH) agonists: medication to temporarily suppress
ovarian function during treatment
𝐁𝐫𝐞𝐚𝐬𝐭 𝐂𝐚𝐧𝐜𝐞𝐫 𝐚𝐧𝐝 𝐅𝐞𝐫𝐭𝐢𝐥𝐢𝐭𝐲 𝐏𝐫𝐞𝐬𝐞𝐫𝐯𝐚𝐭𝐢𝐨𝐧
• 𝐀𝐝𝐝𝐫𝐞𝐬𝐬𝐢𝐧𝐠 𝐟𝐞𝐫𝐭𝐢𝐥𝐢𝐭𝐲 𝐜𝐨𝐧𝐜𝐞𝐫𝐧𝐬 𝐢𝐧 𝐛𝐫𝐞𝐚𝐬𝐭 𝐜𝐚𝐧𝐜𝐞𝐫 𝐩𝐚𝐭𝐢𝐞𝐧𝐭𝐬
• Early fertility consultation
• Assess patient's fertility
• Evaluate treatment impact
• Personalized preservation plan
• 𝐅𝐞𝐫𝐭𝐢𝐥𝐢𝐭𝐲 𝐩𝐫𝐞𝐬𝐞𝐫𝐯𝐚𝐭𝐢𝐨𝐧 𝐦𝐞𝐭𝐡𝐨𝐝𝐬 𝐟𝐨𝐫 𝐛𝐫𝐞𝐚𝐬𝐭 𝐜𝐚𝐧𝐜𝐞𝐫 𝐩𝐚𝐭𝐢𝐞𝐧𝐭𝐬
• Embryo freezing
• Egg freezing
• Ovarian tissue cryopreservation
• Ovary transposition
• GnRH agonist therapy
𝐎𝐯𝐚𝐫𝐢𝐚𝐧 𝐓𝐫𝐚𝐧𝐬𝐩𝐥𝐚𝐧𝐭 𝐚𝐧𝐝 𝐎𝐯𝐚𝐫𝐲 𝐓𝐫𝐚𝐧𝐬𝐩𝐨𝐬𝐢𝐭𝐢𝐨𝐧
• 𝐇𝐨𝐰 𝐭𝐡𝐞𝐬𝐞 𝐩𝐫𝐨𝐜𝐞𝐝𝐮𝐫𝐞𝐬 𝐰𝐨𝐫𝐤
• Ovarian transplant: Cryopreserved tissue reimplanted
• Ovary transposition: Ovaries repositioned surgically
• 𝐁𝐞𝐧𝐞𝐟𝐢𝐭𝐬 𝐚𝐧𝐝 𝐩𝐨𝐭𝐞𝐧𝐭𝐢𝐚𝐥 𝐫𝐢𝐬𝐤𝐬
• Fertility restoration
• Natural hormone production
• Reduces premature menopause
• Surgical complications possible
• Transplant rejection risk
𝐒𝐩𝐞𝐫𝐦 𝐅𝐫𝐞𝐞𝐳𝐢𝐧𝐠: 𝐏𝐫𝐞𝐬𝐞𝐫𝐯𝐢𝐧𝐠 𝐦𝐚𝐥𝐞 𝐟𝐞𝐫𝐭𝐢𝐥𝐢𝐭𝐲
• 𝐓𝐡𝐞 𝐬𝐩𝐞𝐫𝐦 𝐟𝐫𝐞𝐞𝐳𝐢𝐧𝐠 𝐩𝐫𝐨𝐜𝐞𝐬𝐬
• Semen collection
• Semen analysis
• Cryoprotectant addition
• Controlled-rate freezing
• Long-term storage
• 𝐅𝐚𝐜𝐭𝐨𝐫𝐬 𝐚𝐟𝐟𝐞𝐜𝐭𝐢𝐧𝐠 𝐬𝐩𝐞𝐫𝐦 𝐯𝐢𝐚𝐛𝐢𝐥𝐢𝐭𝐲 𝐩𝐨𝐬𝐭-𝐭𝐡𝐚𝐰
• Pre-freeze sperm quality
• Cryoprotectant type
• Freezing/thawing protocols
• Storage duration
• Individual variability
𝐎𝐯𝐚𝐫𝐢𝐚𝐧 𝐓𝐢𝐬𝐬𝐮𝐞 𝐂𝐫𝐲𝐨𝐩𝐫𝐞𝐬𝐞𝐫𝐯𝐚𝐭𝐢𝐨𝐧 (𝐎𝐓𝐂)
• 𝐓𝐡𝐞 𝐫𝐨𝐥𝐞 𝐨𝐟 𝐎𝐓𝐂 𝐢𝐧 𝐟𝐞𝐫𝐭𝐢𝐥𝐢𝐭𝐲 𝐩𝐫𝐞𝐬𝐞𝐫𝐯𝐚𝐭𝐢𝐨𝐧
• Protects fertility by freezing ovarian tissue before medical treatments that may cause infertility.
• Important for prepubertal girls and young women who cannot undergo other fertility preservation
• OTC enables women to postpone childbearing by preserving their fertility potential.
• Ovarian tissue can be transplanted back after medical treatments to restore fertility.
• OTC can be used as a source of natural hormones with premature ovarian failure
• 𝐀𝐝𝐯𝐚𝐧𝐜𝐞𝐦𝐞𝐧𝐭𝐬 𝐢𝐧 𝐎𝐓𝐂 𝐭𝐞𝐜𝐡𝐧𝐢𝐪𝐮𝐞𝐬
• Vitrification
• Vitro maturation:
• Robotic-assisted transplantation:
• Tissue engineering:
• Biomaterials:
𝘿𝙤 𝙡𝙚𝙖𝙫𝙚 𝙮𝙤𝙪𝙧 𝙘𝙤𝙢𝙢𝙚𝙣𝙩𝙨 𝙝𝙤𝙬 𝙙𝙞𝙙 𝙮𝙤𝙪 𝙛𝙞𝙣𝙙 𝙩𝙝𝙚 𝙨𝙚𝙨𝙨𝙞𝙤𝙣 𝙖𝙣𝙙 𝙥𝙡𝙨 𝙛𝙚𝙚𝙡 𝙛𝙧𝙚𝙚 𝙩𝙤 𝙡𝙚𝙖𝙫𝙚 𝙮𝙤𝙪𝙧 𝙦𝙪𝙚𝙧𝙞𝙚𝙨 𝙧𝙚𝙡𝙖𝙩𝙚𝙙 𝙩𝙤 𝙩𝙝𝙚 𝙩𝙤𝙥𝙞𝙘.
You can watch the Part -1 of this Curtain Raiser - 25 here: [ Ссылка ]
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