Modelling SARS-CoV-2 immuno-epidemiology, vaccination, and invasion dynamics of new variants
The COVID-19 pandemic is a global emergency with significant morbidity and mortality. In this talk, we summarize recent modeling that investigates SARS-CoV-2 immuno-epidemiology and the impact of vaccination on potential future landscapes of immunity. Through a general framework, we also explore the potential epidemiological and evolutionary considerations of various vaccine dosing regimes, and we then examine the impact of vaccine nationalism. Using a simple model, we examine the invasion dynamics of SARS-CoV-2 variants and the impacts of vaccine breakthrough infections. Finally, we highlight crucial empirical and theoretical gaps that need to be addressed, and conclude with future outlooks.
Chadi Saad-Roy is a Miller Research Fellow at UC Berkeley. He has a PhD in Quantitative and Computational Biology from Princeton University. Broadly, he is interested in mathematical biology, epidemiology, and evolutionary biology. He has worked on various topics at the interface of these disciplines, including influenza eco-evolutionary dynamics, evolutionary theory for the evolution of an asymptomatic infectious stage, and, during the COVID-19 pandemic, modeling SARS-CoV-2 immuno-epidemiological dynamics.
7 September 2022
