What are the key differences between uncomplicated and complicated typhoid fever?
What is the standard procedure for diagnosing typhoid fever?
How does the course of typhoid fever progress from the initial to the final stages?
What are the risk factors associated with typhoid fever and how can they be mitigated?
How does the Salmonella Typhi bacteria cause typhoid fever?
What is the fatality rate of untreated typhoid fever versus treated typhoid fever?
What treatments are available for typhoid fever and how effective are they?
Important Highlights:

Typhoid fever, a life-threatening systemic infection caused by the Salmonella Typhi bacteria, can be severe and even fatal if left untreated.
The disease has an incubation period of 6 to 30 days and presents in two forms: uncomplicated and complicated, with the latter involving severe complications from the third week of illness.
Typhoid fever mainly affects the gastrointestinal system and progresses in four distinct phases over several weeks, with symptoms ranging from fever and fatigue to severe complications like intestinal hemorrhage or perforation and neurological issues.
The gold standard for diagnosing typhoid fever is a blood culture test in the first week of illness, followed by stool and urine cultures from the second week onwards.
Treatment for typhoid typically involves first-line antibiotics like Fluoroquinolones or third-generation cephalosporins, with second-line treatment like Azithromycin used in cases of allergy or resistance.
Poor sanitation, lack of access to clean water, and exposure in endemic areas are major risk factors for contracting typhoid fever.


By Rosemary A Jones - Own work, CC BY-SA 4.0, [ Ссылка ]

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