Most clinicians have learned along the way that certain opioids are preferred in liver and kidney disease while others should be avoided. Many guidelines suggest reducing starting doses and increasing administration intervals when those organs are impaired. Why is that? This video will discuss opioid metabolism and the implications it has for dose adjustments in liver and kidney disease. I'm not talking about specific dosing recommendations, but about the priniciples that guide those recommendations.
DISCLAIMER: This does not constitute medical advice nor formal medical consultation. If you are a patient, please consult your medical practitioner. If you are a provider please seek professional consultation from others at your institution.
