Isolation Identification and Analysis of Menthol (Pharmacognosy)

MENTHA
Botanical Source
It is the oil obtained by the distillation of Mentha piperita, belonging to family Labiatae.

Chemical Constituents
The chief constituent of Peppermint oil is Menthol, along with other constituents like menthyl acetate, isovalerate, menthone, cineol, inactive pinene, limonene, and other less important bodies. Menthol separates on cooling it to a low temperature (–22°C). The flavouring properties of the oil are due to both the ester and alcoholic constituents, whereas the medicinal value is attributed only due to the alcoholic components. The English oil contains 60 to 70% of Menthol, the Japanese oil containing 85%, and the American has only about 50%.

Uses
It is stimulant, stomachic, carminative, inflatulence, and colic; in some dyspepsia, sudden pains, for cramp in the abdomen and also in cholera and diarrhoea. Oil of peppermint allays sickness and nausea, as infants cordial. Peppermint is good to aid in raising internal heat and inducing perspiration. It is also used in cases of hysteria and nervous disorders.

Adulterants
Camphor oil, Cedarwood oil, and oil of African Copaiba are occasionally used as an adulterant of Peppermint oil, the oil is also adulterated with one-third part of rectified spirit. If adulterated with rectified spirit it can be identified by agitating it with water which produces milkiness. Rosemary oil and Turpentine oil are also sometimes used as adulterants.

Marketed Products
It is one of the ingredients of the preparation known as Dabur lal tooth powder (Dabur).

T. Y. B. Pharm SEM V
BP 504 T Pharmacognosy and Phytochemistry- II

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#pharmacognosy #Methaoil Menthol #extraction #isolation #sufipharm
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#Pharmacognosy #Menthaoil #sufipharm #isolation #Extraction

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