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Atorvastatin
Generic Name: atorvastatin
Trade Name: Lipitor
Indication: management of high cholesterol (hypercholesterolemia), primary prevention of cardiovascular disease
Action: lowers total cholesterol as well as LDL while slightly increasing HDL. Inhibits HMG-CoA reductase which plays a role in the liver in cholesterol formation
Therapeutic Class: lipid-lowering agent Pharmacologic Class HMG-CoA reductase inhibitor Similar Medications simvistatin (Zocor), rosuvastatin (Crestor)
Nursing Considerations:
contraindicated in active liver disease
may cause rhabdomyolysis
monitor renal function
monitor serum cholesterol before, about 4 weeks after starting, and frequently during drug therapy
monitor liver function tests
instruct patient to report muscle weakness (sign of rhabdomyolysis)
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