Earl is a low-life who buys a winning lottery ticket, only to get hit by a car, losing the ticket in the process. He then realizes in the hospital that his bad luck is the result of karma in which fate punishes him for all the rotten things he's ever done in his life; therefore, he then decides to dedicate his life to making amends to all the people he has hurt in his life.

Jason Lee - Earl Hickey,
Ethan Suplee - Randy Hickey,
Jaime Pressly - Joy Turner,
Nadine Velazquez - Catalina,
Eddie Steeples - Darnell Turner,
Louis T. Moyle - Dodge,
Trey Carlisle - Earl Jr.,
Noah Crawford - Young Earl,
Dale Dickey – Patty,

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