Brucella rapid agglutination test : Positive
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Introduction And Principle Of Brucella Agglutination Test
Brucella agglutination test is a serological test for brucellosis. Other serological test for brucellosis are Standard Agglutination test, 2 Marceptoethanol (2ME) Agglutination test, Coombs’ test, Complement fixation , Radioimmunoassay, ELISA and Rose bengal test. Standard agglutination test is very useful because blood culture may not demonstrate the organism for many weeks, the Brucella agglutinin determinations can support a presumptive diagnosis of acute brucellosis. Isolation of the organism, usually from blood, provides definitive proof of infection. Both IgM and IgG antibodies continue to rise during acute stage of infection and this test turns positive 7-10 days after infection. Patients with localized brucellosis may be afebrile and may not have significant levels of Brucella agglutinin titre.The prozone phenomenon ( i.e. absence of agglutination in low dilution of serum due to high conentration of antibodies) is common and results in a negative reaction; this can be prevented by using serial dilutions of the serum.

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