Infectious diseases and chronic inflammatory conditions such as autoimmune diseases, cancer, and transplant rejections, are major causes of illness and death worldwide.

T cells in the immune system help to orchestrate the body’s defense machinery against infection and help to prevent dysregulated immune responses that can lead to chronic inflammatory diseases.

Our lab uses single-cell genomics, molecular biology, virology, immunology, and systems-based approaches to investigate how T cells become different functional regulators during adaptive immunity. We are interested in the molecular mechanisms of T cell differentiation in the immune response to viral infections, as well as in chronic inflammation (e.g., autoimmunity, cancer), and vaccination.

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