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Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration - a 2 minute Preview of the Experimental Protocol
Hwanseok Jang, Jongseong Kim, Jennifer H. Shin, Jeffrey J. Fredberg, Chan Young Park, Yongdoo Park
Korea University, Department of Biomedical Sciences; Korea Advanced Institute of Science and Technology, Department of Mechanical Engineering; Harvard T.H. Chan School of Public Health, Department of Environmental Health;
Collective cell migration in development, wound healing, and cancer metastasis is often guided by the gradients of growth factors or signaling molecules. Described here is an experimental system combining traction microscopy with a microfluidic system and a demonstration of how to quantify the mechanics of collective migration under biochemical gradient.
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