In this video, Patrick Kelly tells the story of aspirin, the iconic painkiller tablet, from its ancient origins with willow bark aspirin to modern pharmacology. Learn how aspirin is prepared from salicylic acid and see how it compares to other popular pain relievers like ibuprofen and Tylenol (acetaminophen/paracetamol).
Since a few people have asked, the shirt is a rugby shirt from @RowingBlazers
☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️
🔗 L I N K S 🔗
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📜 S O U R C E S 📜
Annotated fact checked script on Patreon: [ Ссылка ]
The Drug Hunters (affiliate link) [ Ссылка ]
The Discovery of Aspirin's Antithrombotic Effects (2007) [ Ссылка ]
The first 3500 years of aspirin history from its roots – A concise summary (2019)
[ Ссылка ]
Traveling through time with aspirin, a healing companion (2011) [ Ссылка ]
The discovery of aspirin: a reappraisal (2000)
[ Ссылка ]
Rev Stone Willow paper (1763) [ Ссылка ]
THE LIFE CYCLE OF STERLING DRUG, INC. (2000) [ Ссылка ]
Prostaglandin in the inflammatory response
[ Ссылка ]
Painkillers and prostaglandins (2003) [ Ссылка ]
ASPIRIN IN THE TREATMENT OF VASCULAR DISEASES (1948) [ Ссылка ]
Release of Additional Factors in Anaphylaxis and its Antagonism by Anti-inflammatory Drugs (1969) [ Ссылка ]
1974 Elwood trial [ Ссылка ]
Aspirin as a Therapeutic Agent in Cardiovascular Disease : A Statement for Healthcare Professionals From the AHA (1997) [ Ссылка ]
Pharmacology of ibuprofen [ Ссылка ]
The development of COX2 inhibitors (2003) [ Ссылка ]
Future of COX-2 inhibitors (2005) [ Ссылка ]
VIGOR study (2000) [ Ссылка ]
The sad story of Vioxx, and what we should learn from it (2004) [ Ссылка ]
ISIS-2 (1998) [ Ссылка ]
💻 C O N T A C T 💻
patkellyteaches [at] gmail.com
⌛T I M E S T A M P S ⌛
0:00 intro
0:32 How did Aspirin come from Willow?
8:45 Bayer's Marketing Plan
15:22 Mechanism of Action
17:57 Pharmacology of aspirin
🎵M U S I C🎵
Backed Vibes Clean - Rollin at 5 by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. [ Ссылка ]
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#historyofmedicine #medicalhistory
