Video summary by Sara Schad (Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College)
Original paper: [ Ссылка ]
Antigen stimulation induces a subset of CD4+ and CD8+ T cells to differentiate into CD4+CD8+ T cell subsets gaining in polyfunctional characteristics within the tumor. Monitoring CD4+CD8+ T cells may thus favor the identification and selection of antigen reactive T cells to drive clinical benefit.
Keywords: T cells, Cytotoxicity, Plasticity, Cancer, Tumor
Original paper: [ Ссылка ]
