Several Gram positive and a few Gram negative bacteria secrete powerful poisons called exotoxins that are capable of destroying or injuring host cells.
They tend to be specific in their action, e.g. the exotoxin of Clostridium tetani is a neurotoxin. Other important exotoxin producing pathogens include Clostridium botulinum, Clostridium perfringens, Corynebacterium diphtheriae, enterotoxigenic Escherichia coli (ETEC), Shigella dysenteriae,
and Vibrio cholerae. Toxin produced by enteric pathogens is known as enterotoxin.
The cell walls of Gram negative organisms contain endotoxin (O antigen). Unlike exotoxin, endotoxin is not usually secreted by an organism but is
released only when the organism is destroyed. When endotoxin is released into the blood circulation, the resulting toxaemia may cause rigor, chills, and shock. Endotoxin from some pathogens may also have clotting properties and lead to disseminated intravascular coagulation (DIC). Endotoxin
release may also lead to a marked leucocytosis. In contrast to exotoxin, endotoxin is only weakly antigenic. It is also more heat stable than exotoxin.

Your Queries in the video?
1) What is Exotoxin?
2) What is Endotoxin?
3) What is Toxin?
4) Differences between Exotoxin and Endotoxin?

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