Dr. Gilbert Simoni is an interventional gastroenterologist and natural orifice surgeon in Thousand Oaks, California. Upon receiving his medical degree from the AUC School of Medicine, Dr. Simoni went on to complete his residency in Internal Medicine at Seton Hall University where he was asked to also serve as a Chief Resident. He then went on to complete his Gastroenterology/Hepatology fellowship at Seton Hall University and UMDNJ.
Dr. Simoni’s most cited publication is The TEMPO Trial: a multi-center, randomized, crossover study that took place in several centers of excellence throughout the United States to determine the efficacy of Transoral Incisionless Fundoplication (TIF). Dr. Simoni also serves as a TIF educator and mentor for many surgeons and gastroenterologists around the world. His special areas of interest include the minimally invasive surgical treatment of GERD, Wireless Capsule Endoscopy (WCE), Wireless pH Monitoring, Impedance pH, Endoscopic Mucosal Resection (EMR), Endoscopic Hemorrhoidal Ligation (EHL), Endoscopic Radio Frequency Ablation, and Inflammatory Bowel Disease.
Dr. Simoni founded Advanced Gastroenterology, Inc. (AGI) in 2006, which has been in the spotlight for its patient satisfaction, use of latest technology, and providing the most advanced options available in diagnosis and treatment of digestive conditions. The mission of AGI is to build patient trust and to be the catalyst for a healthier lifestyle through prevention, early detection, and its innovative approach to GI care. The AGI team is also known for its friendly and gentle bedside manner, communication, and responsiveness. The practice is affiliated with multiple hospitals in the area including Los Robles Hospital and Medical Center, West Hills Hospital, Simi Valley Hospital, and St. John’s Regional Medical Center.
Dr. Simoni is also the founder and medical director of the surgical center Advanced Digestive Center of Southern California (ADCSC), where he does most of his outpatient endoscopic procedures.

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