Testosterone Undecanoate - sold as Aveed, Jatenzo, Nebido, and Andriol - is an ester of testosterone that has only recently been approved in the U.S., but has been used outside the country for some time. In its oral form testosterone undecanoate is quickly absorbed in the GI tract, while the intramuscular form is long-acting. In this video I discuss the unique warnings that come with this ester: allergic reaction and pulmonary oil embolism. I also cover how free T, DHT, and SHBG levels may be different vs. more common esters.
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TABLE OF CONTENTS:
01:07 - TESTOSTERONE UNDECANOATE HISTORY
01:43 - FDA has delayed undecanoate approval
02:51 - Oral form recently approved
03:28 - PHARMACOLOGY
- Oral delivery in GI tract bypasses liver first pass
04:12 - Intramuscular form is long-acting, unlike oral
04:49 - SAFETY OF ORAL FORM
- Not liver toxic like oral steroids, used in studies to treat fatty liver
06:38 - Risk of hypertension, comparing risks to other testosterone esters
07:53 - Increase in DHT vs other esters
10:02 - SAFETY OF INTRAMUSCULAR FORM
- Pulmonary oil embolism and allergic reaction: related to tren cough? Other implications
13:03 - IS IT EFFECTIVE?
- Considering effects on Free T, SHBG, and DHT
- T undecanoate ethical considerations?
Stay Strong and Healthy,
Dr. O
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As the Anabolic Doc, since 2003, I’ve provided men who are using or have used anabolic steroids a confidential, ethical and professional medical venue to discuss their use. I do NOT in any way support the use of any performance enhancing drugs - PEDs, anabolic steroid or other medicine for muscle building or body transformation. The “off-label” use of PEDs, as such agents is considered illicit and may lead to adverse health outcomes. Please consult an expert health professional regarding any medical agent and do NOT use any medicine without the explicit advice and supervision of an appropriate medical expert.
This video is for education and information only. This is not medical advice. Only take medications as prescribed by your doctor. Do not take illegal substances. Taking steroids can lead to serious health consequences.
#Undecanoate #TRT #TestosteroneReplacement
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