Presented By: Roy Granit, PhD
Speaker Biography:
Dr. Roy Granit holds a PhD in Biomedical Research with a focus on Genomics and Bioinformatics from the Hebrew University of Jerusalem. He has co-founded two startups in the domains of bioinformatics and natural language processing and has provided consultancy to both academic institutions and the industrial sector, leveraging his extensive knowledge in bioinformatics and machine learning. In 2020, Dr. Granit took the role of Senior Bioinformatics Scientist at Compugen, where he is currently Director and Head of Computational Discovery, leading the interdisciplinary Computational Discovery Group. His group specializes in employing innovative computational approaches to facilitate the discovery of novel immunotherapy drug target candidates.
Webinar: Exploring the immune-tumor microenvironment using high resolution single-cell spatial transcriptomics
Webinar Abstract:
High-resolution spatial transcriptomics stands at the forefront of technological advancements, offering transformative capabilities in the domain of tumor biology research. In this presentation, you will hear about real world examples leveraging this technology to understand the nuances of complex human tumor microenvironment at a spatially resolved single cell level; with a spotlight on DNAM-1 axis immune checkpoint genes currently under evaluation in clinical trials in cancer patients. You will also gain insights into how this technology is successfully used to gain an in-depth look at the DNAM-1 axis in tertiary lymphoid structures. Overall, the findings underscore the immense promise of spatial transcriptomics for deepening the understanding of the tumor microenvironment and to extend the reach of cancer immunotherapies to new patient populations.
Learning Objectives
Explore how high-resolution spatial transcriptomics is revolutionizing tumor biology research with real-world examples and cutting-edge insights.
Uncover the intricacies of the DNAM-1 axis immune checkpoint genes and their impact within the tumor microenvironment, spotlighting current clinical trials.
Gain a comprehensive understanding of the role of spatial transcriptomics in tertiary lymphoid structures, enhancing the reach of cancer immunotherapies to new patient populations.
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