Plum Island, located off the northeastern coast of Long Island, New York, has a rich history spanning centuries. Originally known as "Isle des Plumes" by early French settlers due to its abundant bird population, it later became a haven for pirates and smugglers during the colonial era. In the 19th century, it was used as a quarantine station for diseased livestock, helping prevent the spread of diseases to mainland farms. During World War II, the island was taken over by the U.S. government and used for military purposes. In 1954, the Plum Island Animal Disease Center was established by the U.S. Department of Agriculture, where research on infectious animal diseases, including foot-and-mouth disease, was conducted. Today, the island remains a site of scientific research, though its future is uncertain amidst discussions of potential closure and redevelopment.

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