This is a recording of the Sarcoma Alliance's 2020 Sarcoma Awareness Month Webinar with guest speaker, Dr. William Tseng. Dr. Tseng is a surgical oncologist and member of the Sarcoma Alliance Medical Advisory Board who specializes in retroperitoneal and liposarcomas. In this webinar, Dr. Tseng gives participants an introduction to soft tissue sarcomas and the importance of seeing a sarcoma specialist. Dr. Tseng also answers community questions related to retroperitoneal and liposarcomas (timestamps below).

00:00 - Sarcoma Alliance Introduction with Executive Director Alyssa O’Driscoll
08:01 - Introduction of Guest Speaker, Dr. William Tseng
09:08 - About Dr. Tseng and Dr. Tseng’s work
12:27 - What is Sarcoma?
12:56 - Soft Tissue Sarcoma
15:52 - Soft Tissue Sarcoma Diagnosis & Classification
20:00 - Soft Tissue Sarcoma Subtypes & Distinct Tumor Behavior
21:05 - Soft Tissue Sarcoma Treatment
25:06 - Importance of Seeing a Sarcoma Specialist
26:50 - For the Patient: Resources & Recognition

COMMUNITY QUESTIONS
30:06 - Retroperitoneal Sarcoma: Staging, Treatment, and Outcomes
How do you manage retroperitoneal sarcoma? We hear conflicting opinions.
Is it really possible to stop growth of the mass? What’s the possibility for it to not come back?

42:58 - Liposarocma
--- New treatments of liposarcoma
--- What are the most effective targeted therapies for retroperitoneal liposarcoma reoccurrences? How long are these drugs effective?

50:51 - What are the issues regarding a curative surgery attempt to treat a first local retroperitoneal recurrence where a biopsy (due to location) is not possible, practically timing of such a surgery? How long should one wait to get a better understanding of tumor biology?

53:50 - If a RetroPeritoneal LP, WD tumor is inoperable and the patient can’t have chemo/radiation, considering variables (age, lifestyle, etc), what are the symptoms the patient will have? How does the patient die?

56:16 - What is the best surgery for leiomyosarcoma hysterectomy..full abdominal or laparoscopic?

57:56 How does an abdominal mesh impact a resection?

59:59 - If a patient has RLMS that has metastasized, can surgery be still considered or the systemic is the best approach?

1:03:48 - When there is no hope for clear margins, can you negotiate ablation of organs such as the 2nd adrenal / 1st one already taken?

01:04:39 - Mixoid liposarcoma: Recurrence to abdomen; Trabectedin kept tumors stable for 18 months then one tumor grew 4 cms in 4 months. Recent surgery removed the tumor in abdomen and one unexpected tumor. Currently no sign of tumor. Would follow-up chemo be useful?

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