🔷"Pearl necklace sign" explosion?🔷
🔷Macular hole🔷
🔶OCT Clinical Case Series🔶
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🟢 Pearl necklace sign detected with SD-OCT is characterized by a contiguous ring of small hyperreflective dots lining in the inner wall of cystoid spaces located in the Outer Plexiform Layer. It is considered that it may represent lipid-laden macrophages.
🟢 The pearl necklace sign should be distinguishing from Outer retinal tubulation (ORT), which is located deeper in the outer nuclear layer of the retina.
🟢 In ORT, the hyperreflective ring is continuous and homogeneous, while as the contiguous hyperreflective dots are as small foci in the pearl necklace sign. Both entities have also different pathogenesis.
🟢 It is considered that ORT might be a result of focal disruption of the photoreceptor layer.
👤 J.R. Fontenla, MD-PhD.
🏨 Hospital Clinic of Barcelona
👁 YouTube.com/@VisualSystem
🏛 University of Barcelona
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